Status:

RECRUITING

Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics

Lead Sponsor:

Zhujiang Hospital

Conditions:

Arterial Aneurysm Wall Enhancement on HRMRI

Eligibility:

All Genders

18-80 years

Brief Summary

This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemod...

Eligibility Criteria

Inclusion

  • Age 18-80 years old, male or infertile female;
  • Diagnosed as IA (intracranial aneurysm) through CTA, MRA, or DSA; And it is suitable for endovascular intervention treatment
  • The patient and/or their legal representative or guardian fully understand the research purpose, voluntarily participate and sign informed consent Books;
  • Patients willing to cooperate with high-resolution magnetic resonance imaging.
  • Patients willing to follow up and evaluate according to clinical research protocol requirements

Exclusion

  • AVM (arteriovenous malformation), Moyamoya disease, or DAVF (dural arteriovenous fistula) related aneurysms;
  • Patients with contraindications for high-resolution magnetic resonance imaging;
  • Participants in clinical trials of other drugs or medical devices;
  • Patients with severe underlying diseases and extremely poor clinical conditions who cannot tolerate general anesthesia surgery;
  • Patients with poor compliance and inability to cooperate with follow-up;
  • Possible or clear history of severe allergy to contrast agents;
  • Patients with a life expectancy of less than 2 years;
  • Women who are breastfeeding and preparing for pregnancy during the study period

Key Trial Info

Start Date :

January 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT06539767

Start Date

January 1 2023

End Date

December 31 2025

Last Update

July 28 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Zhujiang Hospital

Guangzhou, Guangdong, China

2

Southern medical university, zhujiang hospital

Guangzhou, China