Status:
NOT_YET_RECRUITING
The Relationship Between Serum Chemokine Ligand 21 (CCL-21) Level and Disease Activity
Lead Sponsor:
Gaziosmanpasa Research and Education Hospital
Conditions:
Rheumatoid Arthritis
Osteoarthritis
Eligibility:
All Genders
16-60 years
Brief Summary
Rheumatoid arthritis (RA) is a chronic systemic disease characterized by the development of new capillaries involved in the infiltration of inflammatory cells causing synovial hyperplasia and progress...
Detailed Description
Rheumatoid arthritis (RA) is a chronic systemic disease characterized by the development of new capillaries involved in the infiltration of inflammatory cells causing synovial hyperplasia and progress...
Eligibility Criteria
Inclusion
- 20 RA patients, 20 Osteoarthritis patients and 20 healthy volunteers between the ages of 16-60.
Exclusion
- Age \< 16 years,
- Systemic Disorders (Diabetes, Hematological diseases (coagulopathies), serious cardiovascular diseases, chronic liver and kidney disease or malignancy.)
- Patients suffering from infectious disorders (septic arthritis, viral arthritis, fungal arthritis and other rheumatic diseases such as spondyloarthropathies, systemic lupus erythematosus or dermatomyositis and others.)
- Individuals with other autoimmune diseases, malignancy, cardiac or neurological deficits, end-stage organ failure and other conditions that may affect the serum level of CCL21, such as diabetes mellitus, concomitant inflammatory disease (acute infection or chronic inflammatory state), coronary artery disease and hepatitis, were excluded from the study. was left
- Lymphadenopathies
- OA patients who received intra-articular injection or systemic glucocorticoid therapy within 3 months were excluded from the study.
Key Trial Info
Start Date :
August 12 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06540573
Start Date
August 12 2024
End Date
November 30 2024
Last Update
August 6 2024
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