Status:
COMPLETED
Analysis of Pregnancy-Associated Plasma Protein-A and Interleukin-6 Gene Polymorphisms in Patients With Periodontitis
Lead Sponsor:
Marmara University
Conditions:
Periodontitis
Polymorphism, Restriction Fragment Length
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study is to evaluate the relationship between pregnancy associated plasma protein-A (PAPP-A) and interleukin-6 (IL-6) gene polymorphisms and stage 3 grade B and C (S3GBC) periodontitis...
Detailed Description
A total of 226 systemically healthy subjects, consisted of 112 S3GBC periodontitis patients (P group) and 114 periodontally healthy individuals (H group) were included in our study. Clinical and demog...
Eligibility Criteria
Inclusion
- Participants were eligible for inclusion if they were; systemically healthy non-smokers had not undergone periodontal treatment in the past 6 months had not used antibiotics or anti-inflammatory drugs in the preceding 3 months had not used any medication that could affect periodontal tissues in the past 6 months were 18 years of age or older were not pregnant, and were not lactating.
Exclusion
- The samples taken cannot be stored under appropriate conditions and are damaged.
- The onset of a systemic disease in a systemically healthy individual.
Key Trial Info
Start Date :
December 2 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 28 2024
Estimated Enrollment :
226 Patients enrolled
Trial Details
Trial ID
NCT06540755
Start Date
December 2 2022
End Date
January 28 2024
Last Update
August 6 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Marmara University Dental Faculty Periodontology Departmen
Istanbul, Turkey (Türkiye)