Status:
RECRUITING
Balance, Autonomic Response, and Sensory Modulation to Dosage of Mechanical Vagal Stimulation in Healthy Adults
Lead Sponsor:
University of Vienna
Conditions:
Vagus Nerve Autonomic Disorder
Heart Rate
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The vagus nerve (VN) plays a crucial role in regulating vital functions (heart rate, blood pressure, digestion, and immune response) and maintaining communication between internal organs and the brain...
Detailed Description
mechanical VNs in humans, induced by a combination of non-painful physiological neck movements, effectively reduces the HR at rest in humans, without any side effects in the short- and long-term. Inde...
Eligibility Criteria
Inclusion
- agreement to participate by signing the informed consent form, being 18-60 years old, and sober
Exclusion
- participants having significant neck pain, headache, or leg pain \[with Numeric Pain Rating Scale (NPRS) greater than 3/10\],
- pregnancy
- recent neck or cardiovascular surgery or significant trauma in the preceding 3 months
- diagnosis of cancer or inflammatory disorders (fever),
- spinal cord or cauda equina signs,
- widespread neurological disorders affecting the tone of the limbs and neck muscles
- underlying diseases, such as diabetes mellitus.
- pace-maker
- antibiotic prescription during the last 3 months
- gastrointestinal surgery,
- lower extremity injury (acute or overuse) that prevented them from participating in sports activities for at least one day in the previous 6 months.
Key Trial Info
Start Date :
December 2 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2025
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT06541808
Start Date
December 2 2024
End Date
September 30 2025
Last Update
December 5 2024
Active Locations (1)
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1
UVienna
Vienna, Vienna, Austria, 1090