Status:
RECRUITING
Azithromycin Before Induction
Lead Sponsor:
Arrowhead Regional Medical Center
Conditions:
Infections
Eligibility:
FEMALE
18-45 years
Phase:
PHASE1
Brief Summary
This is a double blinded randomized control trial involving administration of 2 grams prophylactic azithromycin in third trimester patients undergoing induction of labor at our institution to demonstr...
Detailed Description
Induction rates have more than tripled in the last quarter century, and even more in the past five years in light of evidence that the 39th week is the optimal gestational age for birth. Inductions ar...
Eligibility Criteria
Inclusion
- • Third trimester of pregnancy defined as 28 0/7 weeks or more
- Singleton pregnancy
- Age 18-45
- Induction of labor initiated for medical or obstetrical reason or electively over 39 weeks of gestation
- No contraindication to vaginal delivery
- Reassuring fetal heart rate tracing
- Able and willing to provide informed consent
Exclusion
- • Does not read or write in English or Spanish
- Unable or unwilling to give informed consent
- Use of antibiotic or antiviral agent within the last 7 days
- Evidence of active infection at the time of initiation of induction (patients with rectovaginal group B streptococcus positive results will be allowed to participate as it is a colonizing organism, unless they show evidence of active infection)
- Incarcerated Women
- Active substance abuse
- Age \< 18
Key Trial Info
Start Date :
August 7 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 7 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06543290
Start Date
August 7 2023
End Date
August 7 2026
Last Update
September 12 2025
Active Locations (1)
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1
Arrowhead Regional Medical Center
Colton, California, United States, 92324