Status:

RECRUITING

Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease

Lead Sponsor:

Beijing Tiantan Hospital

Conditions:

PD - Parkinson's Disease

Deep Brain Stimulation

Eligibility:

All Genders

50-80 years

Phase:

NA

Brief Summary

Under regional anesthesia, subthalamic nucleus deep brain stimulation (STN-DBS) has proven to be an effective therapeutic approach for improving motor symptoms in Parkinson's disease. However, a signi...

Detailed Description

Regional anesthesia for subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment method for improving motor symptoms in Parkinson's disease. However, the majority of Parkinson's ...

Eligibility Criteria

Inclusion

  • 50-80 years old, ASA grade II-III; 2.Bilateral STN-DBS of patients with Parkinson's disease; 3.Signed informed consent.

Exclusion

  • Obstructive sleep apnea;
  • BMI \> 30kg/m2;
  • Estimated difficult airway;
  • Severe preoperative anxiety;
  • Serious dysfunction of important organs (i.e. heart failure, renal or liver dysfunction)
  • A history of allergy to the anaesthetics.

Key Trial Info

Start Date :

August 9 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 31 2026

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT06543563

Start Date

August 9 2024

End Date

January 31 2026

Last Update

August 9 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100070