Status:
RECRUITING
Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial Hypertension
Lead Sponsor:
University of Pennsylvania
Conditions:
Pulmonary Arterial Hypertension
Frailty
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the study is to learn more about how low-resistance training impacts frailty and the quality of life of people with pulmonary arterial hypertension (PAH). Low-resistance training is an ...
Detailed Description
Patients with pulmonary arterial hypertension and their caregivers will be asked to participate in the study. The study consists of a baseline in-person visit (week 1) where quality of life and physic...
Eligibility Criteria
Inclusion
- Diagnosis of PAH: idiopathic, heritable, associated with connective tissue disease, congenital heart disease, human immunodeficiency virus, drug- or toxin, or portopulmonary hypertension
- On stable PAH therapy for 3 months
Exclusion
- World Health Organization (WHO) functional class IV
- Left ventricular ejection fraction \< 40% (via transthoracic echocardiogram (TTE) within one year of screening)
- Moderate or severe concomitant lung disease: Chronic Obstructive Pulmonary Disease (COPD) or interstitial lung disease
- Enrollment in a clinical trial
- Recent hospitalization (within 4 weeks of screening)
- Inability to perform the Short Physical Performance Battery or wheelchair bound
Key Trial Info
Start Date :
September 4 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06543745
Start Date
September 4 2024
End Date
March 1 2026
Last Update
November 3 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Pennsyvania
Philadelphia, Pennsylvania, United States, 19103