Status:

RECRUITING

Effectiveness and Safety of At-home Gait Rehabilitation Using Wearable Exoskeletal Robot

Lead Sponsor:

Yonsei University

Conditions:

Stroke

Gait, Spastic

Eligibility:

All Genders

19-79 years

Phase:

PHASE4

Brief Summary

The goal of this clinical trial is to evaluate the effectiveness and safety of a home-based robotic-assisted gait rehabilitation service using a wearable exoskeletal robot for stroke patients. The ma...

Detailed Description

After obtaining informed consent, a screening test is conducted. The screening test includes a review of the participant's baseline symptoms and signs, medical history, and medication usage, followed ...

Eligibility Criteria

Inclusion

  • adults aged 19 to 79 years (based on the age on their national ID at the time of consent)
  • individuals diagnosed with cerebral infarction or intracerebral hemorrhage confirmed by MRI or CT.
  • patients who have passed at least one month since stroke diagnosis.
  • individuals exhibiting spastic hemiplegic gait patterns due to stroke.
  • patients with a Functional Ambulatory Category score of less than 4.
  • individuals who can sit on the edge of a bed without assistance and stand for 10 seconds with or without assistance.
  • individuals with sufficient cognitive ability to follow simple instructions and understand the study's content and purpose (Mini-Mental State Examination score \>= 20)

Exclusion

  • individuals with severe joint contractures or osteoporosis, or untreated fractures that contraindicate weight-bearing on the lower limbs.
  • individuals with skin conditions or open wounds that prevent device usage.
  • individuals with significant differences in leg length.
  • individuals with severe deformities or joint contractures in the lower limbs.
  • individuals at high risk of fractures due to conditions like osteoporosis.
  • individuals unable to maintain a sitting or standing position independently.
  • individuals with severe lower limb spasticity (Modified Ashworth Scale grade 2 or higher).
  • individuals with severe cognitive impairment (Mini-Mental State Examination score \< 20), delirium, or severe language impairment that hinders cooperation with wearable exoskeletal robot gait training.
  • individuals unable to maintain prolonged standing or walking due to conditions like orthostatic hypotension or cardiopulmonary impairment.
  • individuals with conditions affecting gait, such as peripheral neuropathy, Parkinsonism, or those with alcohol dependence or severe diabetes.
  • pregnant women or those who could become pregnant.
  • individuals participating in other clinical trials.
  • individuals at high risk of falls or bleeding due to conditions like coagulopathies.
  • individuals shorter than 140 cm, taller than 190 cm, or weighing over 80 kg.
  • individuals with other clinical findings deemed inappropriate for the study by the principal investigator or study coordinator.

Key Trial Info

Start Date :

August 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2026

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT06543758

Start Date

August 1 2024

End Date

July 31 2026

Last Update

November 19 2024

Active Locations (1)

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Yongin Severance Hospital

Yongin-si, Gyeonggi-do, South Korea, 16995