Status:
NOT_YET_RECRUITING
Frequency and Risk Factors of Bleeding in Patients With Chronic Kidney Disease Receiving Anticoagulants
Lead Sponsor:
Sohag University
Conditions:
Chronic Kidney Diseases Receiving Anticoagulants
Eligibility:
All Genders
Brief Summary
1-Introduction: Chronic kidney disease (CKD) is a significant global public health issue, closely linked to cardiovascular disease (CVD). Moreover, CKD is acknowledged as an independent risk factor fo...
Eligibility Criteria
Inclusion
- • Patients with CKD who required and are currently receiving anticoagulation therapy according to the last guidelines, like: Patient was diagnosed with acute DVT, and or pulmonary embolism, and or splanchnic venous thrombosis.
- Mechanical heart valve,
- Prevention of stroke and systemic embolism in nonvalvular AF with at least one stroke risk factor :
- Prior stroke (ischaemic or unknown type), transient ischaemic attack (TIA) or non-central nervous system (CNS) systemic embolism.
- Age ≥ 75 years.
- Hypertension. iv. Diabetes mellitus.
- Heart failure and/ or left ventricular EF ≤ 35%.
- Patients with CKD ( maintenance or not on hemodialysis)
- Willing and agreed to be included in the study
Exclusion
- • Significant inherited or acquired bleeding disorder
- Patient with family history of bleeding tendency
- Patient with contraindication to use anticoagulants
- Clinically significant active bleeding
- Hepatic disease with associated coagulopathy including Child-Pugh C
- Lesions or conditions at significant risk of bleeding including intracranial hemorrhage unless under the advice of a neurologist/neurosurgeon
- Pregnancy, and lactating patient or suspected of pregnancy,
- Incapable of consenting
Key Trial Info
Start Date :
September 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06543927
Start Date
September 1 2024
End Date
February 1 2025
Last Update
August 9 2024
Active Locations (1)
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1
Sohag university Hospital
Sohag, Egypt