Status:
RECRUITING
Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension
Lead Sponsor:
Medical University of Vienna
Conditions:
Idiopathic Intracranial Hypertension
Eligibility:
All Genders
18-90 years
Brief Summary
The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension. For this purpose, optic nerve head blood flow will be examin...
Detailed Description
Idiopathic intracranial hypertension (IIH) is a neuroophthalmological disease, characterized by an increased intracranial pressure (ICP) without an identifiable causative factor. If not properly treat...
Eligibility Criteria
Inclusion
- Inclusion criteria for patients with idiopathic intracranial hypertension
- Men and Women aged ≥ 18 years
- Signed informed consent
- Newly diagnosed idiopathic intracranial hypertension or relapse of idiopathic intracranial hypertension
- Non-Smokers
- Inclusion criteria for healthy age- and sex-matched control subjects
- Men and Women aged ≥ 18 years
- Signed informed consent
- Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant
- Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant
- Non-Smokers
- Exclusion criteria for patients with idiopathic intracranial hypertension and healthy age- and sex-matched control subjects:
- Blood donation in the three weeks preceding the study
- Symptoms of a clinically relevant illness in the three weeks preceding the study
- Ocular inflammation or infection within the last 3 months
- History or family history of epilepsy
- Diabetes mellitus type 1 or type 2
- History or known presence of other cerebral vascular diseases (e.g.: arteriovenous malformation, aneurysm, major artery stenosis or occlusion)
- History or known presence of intracranial infections (e.g.: meningitis)
- History or known presence of other neurological diseases (e.g.: brain tumor, hydrocephalus, degenerative diseases)
- Patients receiving corticosteroids or immunosuppressant therapy
- Pregnant or breast-feeding women
- Women of childbearing potential (neither menopausal, nor hysterectomized, nor sterilized) not using effective contraception
Exclusion
Key Trial Info
Start Date :
May 28 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT06545981
Start Date
May 28 2024
End Date
August 31 2026
Last Update
August 30 2024
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, 1090