Status:

RECRUITING

Gut Microbiota-dependent Health Impacts of Haskap Berries

Lead Sponsor:

Montana State University

Collaborating Sponsors:

Montana State Agricultural Experiment Station

Conditions:

Metabolic Disease

Inflammation

Eligibility:

All Genders

35-65 years

Phase:

NA

Brief Summary

Polyphenol-rich Haskap berries (Haskap) have untapped therapeutic potential to improve human health, and agricultural producers in northern U.S. states are poised to increase production if consumer de...

Detailed Description

The long-term goal of this project is to form a partnership linking the health impacts of Haskap varieties and management practices that maximize health-promoting compounds to benefit both consumers a...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Metabolically Healthy Group:
  • All of the following:
  • Waist circumference: men ≤ 40, women ≤ 35 inches
  • Systolic blood pressure: ≤ 130 mmHg
  • Diastolic blood pressure: ≤ 85 mmHg
  • Fasting glucose: ≤ 100 mg·dl-1
  • Fasting triglycerides: ≤ 150 mg·dl-1
  • HDL: men \> 40, women \> 50 mg·dl-1
  • Inclusion Criteria for Metabolically Unhealthy Group:
  • Required:
  • \- Waist circumference: men ≥ 40, women ≥ 35 inches
  • AND ≥ 1 of the following:
  • Systolic blood pressure: \> 130 mmHg
  • Diastolic blood pressure: \> 85 mmHg
  • Fasting glucose: \> 100 mg·dl-1
  • Fasting triglycerides: \> 150 mg·dl-1
  • HDL: men ≤ 40, women ≤ 50 mg·dl-1
  • Exclusion Criteria:
  • BMI \<18 or \> 40 kg/m\^2
  • potential allergy to Haskap or placebo ingredients
  • use of anti-inflammatory, lipid lowering, glucose lowering, blood pressure, or any other medications that may interfere with study measures
  • pregnant or lactating woman
  • diagnosis with type 1 or type 2 diabetes or any other condition that may interfere with study measures
  • smoke cigarettes
  • have taken antibiotics in the past 90 days
  • take supplements including pre/probiotics or "superfoods" within 30 days of starting the study
  • are planning on starting a weight loss or exercise regiment change
  • follow a specific diet such as low carbohydrate, vegan, and vegetarian
  • consume over 5 servings of fruit/vegetables per day
  • are unwilling to reduce caffeine intake to one 8 oz serving per day for the durations of the study

Exclusion

    Key Trial Info

    Start Date :

    February 26 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 1 2028

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT06546020

    Start Date

    February 26 2025

    End Date

    May 1 2028

    Last Update

    April 2 2025

    Active Locations (1)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (1 locations)

    1

    Montana State University

    Bozeman, Montana, United States, 59717

    Gut Microbiota-dependent Health Impacts of Haskap Berries | DecenTrialz