Status:
RECRUITING
Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced Abortion
Lead Sponsor:
Women's Hospital School Of Medicine Zhejiang University
Conditions:
Pregnancy Complications
Eligibility:
FEMALE
18-40 years
Phase:
PHASE1
Brief Summary
Induced abortion is a common method to terminate pregnancy, but during the operation, it is necessary to dilate the cervix and aspirate the uterine cavity. Repeated induced abortions may increase the ...
Detailed Description
Postoperative care after induced abortion should prioritize the issue of endometrial repair. In 2021, the Family Planning Branch of the Chinese Medical Association published the "Expert Consensus on P...
Eligibility Criteria
Inclusion
- Age between 18 years old (inclusive) and 40 years old (inclusive)
- Body Mass Index (BMI) ranging from 18.5Kg/㎡ to 23.9Kg/㎡
- Experienced at least 2 abortions or had a missed abortion
- Confirmed gestational age of no more than 10 weeks, and the ultrasonic examination within three days prior to the surgery shows a gestational sac (average of three diameters) of at least 1.0cm, with an embryo length of no more than 3.0cm
- Normal preoperative examination results as per the "Clinical Diagnosis and Treatment Guidelines and Technical Operation Standards: Family Planning Volume (2017 Revision)"
- Capable of regular follow-ups and willing to sign the informed consent form.
Exclusion
- Individuals with contraindications to estrogen and progesterone therapy
- History of uterine adhesions confirmed by hysteroscopy, or a history of uterine cavity surgery or uterine malformation correction
- Subjects who require placement of an intrauterine device or administration of oral contraceptives or subcutaneous implants after the procedure
- Individuals with mental status or cognitive function abnormalities who are unable to cooperate with the treatment process
- Subjects who, in the opinion of the investigator, have potential risks or any other factors that may interfere with the study.
Key Trial Info
Start Date :
May 9 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06546397
Start Date
May 9 2024
End Date
December 31 2025
Last Update
August 28 2025
Active Locations (1)
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1
Women's Hospital School Of Medicine Zhejiang University
Hangzhou, Zhejiang, China, 310006