Status:

COMPLETED

Study on Treating by Eating: Role of AGEs on Mucosal Barrier and Microbiome.

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Collaborating Sponsors:

Vlaams Instituut voor Biotechnologie (VIB)

Conditions:

Healthy

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This is an exploratory study aimed at healthy volunteers to investigate the impact of differential cooking methods on global and gut inflammation, intestinal permeability, and the gut microbiota. The ...

Detailed Description

This is a pilot project aimed at healthy volunteers to investigate the impact of differential cooking methods on systemic and intestinal inflammation, permeability, and the gut microbiota, using a ran...

Eligibility Criteria

Inclusion

  • Overall healthy
  • Adhering to an omnivorous diet
  • Body Mass Index (BMI) between 18.5 - 30 kg/m2
  • Able to provide consent.

Exclusion

  • Participants with chronic illnesses including diabetes mellitus, cardiovascular disease, or cancer; eating disorders, irritable bowel syndrome; inflammatory bowel diseases, and previous bowel surgery (except for appendectomy).
  • Current smoking
  • Participants taking nonsteroidal anti-inflammatory drugs (NSAIDS), proton pump inhibitors, antacids, or laxatives one month before enrollment or antibiotics, prebiotics or probiotics six months before the start of the trial.
  • Pregnancy of lactation

Key Trial Info

Start Date :

February 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 30 2022

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06547190

Start Date

February 1 2022

End Date

July 30 2022

Last Update

August 9 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

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University Hospital of Leuven

Leuven, Belgium