Status:
COMPLETED
Exparel Versus Bupivacaine in Post-operative Pain Control
Lead Sponsor:
Case Western Reserve University
Conditions:
Liposomal Bupivacaine
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
This is a prospective, randomized study to evaluate anaesthetic parameters, postoperative analgesia and oral analgesic consumption comparing exparel (liposomal bupivacaine) vs. standard bupivacaine
Detailed Description
The main purpose of this prospective, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and oral analgesic consumption comparing exparel (liposomal bupivacaine) vs. stan...
Eligibility Criteria
Inclusion
- Male and nonpregnant female adults (≥18 years of age) with American Society of Anesthesiologists physical status classification 1, 2, or 3 who were scheduled to undergo bilateral third molar extraction (extraction of all 4 third molars) under local anesthesia and general anesthesia Study participants were required to have full or partial bony impaction of both mandibular third molars.
Exclusion
- history of allergy or contraindication to amide-type local anesthetics, epinephrine, or opioids a history of any disease or condition or recent use of any drug that, in the opinion of the investigator, might increase the risk of surgery or interfere with study evaluations any use of long-acting opioids, nonsteroidal anti-inflammatory drugs, aspirin, or acetaminophen within 3 days before screening or use of opioids within 24 hours of screening Patient that is pregnant or suspected to be pregnant Adults that cannot speak English, adults that are unable to consent on their own, or persons that are listed as vulnerable individuals will not be part of the study
Key Trial Info
Start Date :
August 21 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2025
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT06547255
Start Date
August 21 2024
End Date
July 1 2025
Last Update
August 5 2025
Active Locations (1)
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1
Case Western Reserve University
Cleveland, Ohio, United States, 44106