Status:
RECRUITING
Dietary Intervention on Atopy
Lead Sponsor:
National University of Singapore
Conditions:
Atopic Dermatitis
Atopic
Eligibility:
All Genders
21-65 years
Phase:
NA
Brief Summary
Dietary habits play an indispensable role in maintaining overall health and well-being. In recent years, emerging research has underscored the importance of dietary factors on a range of diseases whic...
Detailed Description
Atopic dermatitis (AD) is a chronic inflammatory skin disease highly associated with xerosis and pruritus, affecting a substantial portion of individuals of all age groups. The European Academy of All...
Eligibility Criteria
Inclusion
- Presence of current, mild-to-moderate atopic dermatitis/eczema at flexural areas
- 21 to 65 years of age (inclusive) at screening
- Must be English-literate and able to give informed consent in English
- Be residing in Singapore and will not be travelling outside of Singapore during the study period
- Reliable and willing to follow study procedures and be available for the duration of the study
- Non-smokers (tobacco and e-cigarette)
- Non-drinker (no regular or frequent consumption of alcohol)
- Overtly healthy with no pre-existing medical conditions (e.g., diabetes, hypertension, cancer, blood disorders, degenerative/liver/autoimmune/immune/renal diseases, or psychiatric conditions)
- No food allergies to test foods
- No needle phobia
- Be willing to not apply any moisturiser, cosmetics, and/or topical cream on the skin throughout the entire duration of the study.
Exclusion
- Concurrent participation in other research studies
- Pregnancy or lactating individuals
- Known or ongoing psychiatric disorders within 3 years
- Known severe nutritional deficiency
- Vegetarian/vegans (as meat will be included in the diet)
- Individuals who made a significant dietary change in the past 12 months
- Having a pre-existing dietary restriction that would interfere with the adherence to a whole diet meal
- Regular use of strong medication (western and/or traditional), therapies, and alternative medications
- Regular nutritional supplements in the past 12 months Regular consumption of oral contraceptive pills and/or steroid hormones
- Antibiotic use in the past 2 months
- Any long-term hospitalisation or surgery during the 6 months before enrolment in study
- Significant change in weight (+/- 5.0%) during the past month
- History of bleeding diathesis or coagulopathy (or any bleeding disorders)
- Having donated blood of more than 500 mL within 4 weeks of study enrolment
Key Trial Info
Start Date :
May 10 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06547372
Start Date
May 10 2024
End Date
April 30 2025
Last Update
August 9 2024
Active Locations (1)
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1
National University of Singapore
Singapore, Singapore, 118177