Status:

NOT_YET_RECRUITING

Papaverine and Oxytocin vs Oxytocin Alone in Labor Induction

Lead Sponsor:

Western Galilee Hospital-Nahariya

Conditions:

Induced; Birth

Labor Onset and Length Abnormalities

Eligibility:

FEMALE

18-50 years

Phase:

NA

Brief Summary

This study aims to evaluate the efficacy and safety of combining papaverine with oxytocin for labor induction compared to oxytocin alone

Detailed Description

Labor induction is a common obstetric procedure aimed at stimulating uterine contractions to initiate labor, often due to medical or obstetric indications such as post-term pregnancy, preeclampsia, or...

Eligibility Criteria

Inclusion

  • Women with a singleton pregnancy Over the age of 18 Term (between 37-42 weeks of gestation) A medical decision for labor induction using oxytocin. Cephalic presentation Viable fetus nulliparity

Exclusion

  • parity \>1
  • Twin pregnancy Women with a previous cesarean section Severe fetal anomalies Women with psychiatric disorders, including depression and schizophrenia. Contraindication to vaginal delivery Women unable to sign the consent form Women known to have SVT (supraventricular tachycardia). Women with a heart rate over 100 or arrhythmia Known sensitivity to any component of the drug Liver disease

Key Trial Info

Start Date :

September 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT06547437

Start Date

September 1 2024

End Date

December 1 2025

Last Update

September 19 2024

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