Status:

RECRUITING

Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy

Lead Sponsor:

Vastra Gotaland Region

Conditions:

Proliferative Diabetic Retinopathy

Diabetic Retinopathy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP). In current clinical...

Detailed Description

Proliferative diabetic retinopathy (PDR) is a well-known complication for both type 1 and type 2 diabetes mellitus (DM) and it is the leading cause for blindness in working-age adults. The current gol...

Eligibility Criteria

Inclusion

  • Age \> 18 years.
  • Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.
  • Visual acuity ≥ 0.1 Snellen.
  • CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.
  • Clear media and adequately dilated pupil for PRP.

Exclusion

  • Intraocular surgery within the last 4 months or planned within the next 3 months.
  • Previous or current center-involved diabetic macular edema (Ci-DME).
  • Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.
  • Treatment with medications known to risk macular edema.
  • Media opacity preventing adequate PRP.
  • General medical condition making office laser treatment very difficult or impossible.

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2030

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06549023

Start Date

January 1 2025

End Date

December 31 2030

Last Update

November 18 2025

Active Locations (1)

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Ögonmottagning Mölndal/SU

Mölndal, Sweden, 43130