Status:

WITHDRAWN

High Or Low Dose pOstpartUm Oxytocin at the Time of Cesarean Birth

Lead Sponsor:

University of Chicago

Collaborating Sponsors:

Medical College of Wisconsin

Conditions:

Postpartum Hemorrhage

Pregnancy Complications

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

This is a study to investigate whether it is feasible to conduct a randomized controlled trial (RCT) of a high dose of oxytocin versus the standard low-dose oxytocin. Further the investigators, aim to...

Detailed Description

Due to risks of postpartum hemorrhage, defined by the American College of Obstetricians and Gynecologists, as an estimated or quantitative blood loss of greater than 1000 milliliters, uterotonics, or ...

Eligibility Criteria

Inclusion

  • Inclusion criteria.
  • Age 18 or greater
  • English or Spanish speaking
  • Individuals undergoing a scheduled or unscheduled cesarean delivery
  • Exclusion criteria
  • Patient on therapeutic anticoagulation
  • Patient with hypertensive disorder of pregnancy or chronic hypertension
  • Patient with preexisting bleeding disorder
  • Patient with preexisting cardiac disease
  • Patient with severe asthma, defined as the need for two or more agents for disease control, or bronchospasm
  • Patient undergoing planned cesarean hysterectomy

Exclusion

    Key Trial Info

    Start Date :

    October 1 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2026

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT06550089

    Start Date

    October 1 2024

    End Date

    December 1 2026

    Last Update

    December 10 2024

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