Status:

NOT_YET_RECRUITING

Effects of tDCS and VNS on Postoperative Analgesia

Lead Sponsor:

Columbia University

Conditions:

Acute Postoperative Pain

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study seeks to evaluate the efficacy of transcranial direct current stimulation (tDCS) and Afferent Vagus nerve simulation (VNS) in treating acute postoperative pain of patients in the post-anest...

Detailed Description

Two nonpharmacologic interventions have shown promise in treatment of chronic pain. Afferent Vagus nerve simulation (VNS) can modulate nociception, even though the exact mechanism is unclear. Clinical...

Eligibility Criteria

Inclusion

  • Adults aged 18 years or above with the capacity to provide informed consent who are undergoing an elective surgery requiring general anesthesia

Exclusion

  • cardiac bradyarrhythmia: taking beta-blockers;
  • patients with metal implants around the chest, neck, or head (e.g. implantable pacemakers and defibrillators, deep brain stimulation devices);
  • pregnancy
  • history of epilepsy or seizures.
  • patients undergoing surgical procedures involving the head, neck or spine, or those requiring the use of cardiopulmonary bypass

Key Trial Info

Start Date :

August 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06554067

Start Date

August 1 2024

End Date

August 1 2026

Last Update

August 14 2024

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