Status:

ACTIVE_NOT_RECRUITING

THRIVE Improves Early Postoperative Atelectasis in Long-Time Non-Tracheal Intubation Anesthesia for Gastrointestinal Endoscopy: a Clinical Study

Lead Sponsor:

Northern Jiangsu People's Hospital

Conditions:

Early Postoperative Atelectasis

Eligibility:

All Genders

Phase:

NA

Brief Summary

This study aims to explore the clinical effect of THRIVE in improving early postoperative atelectasis in patients undergoing long-term non-intubated anesthesia gastrointestinal endoscopy.

Eligibility Criteria

Inclusion

  • Multiple polyps resection, ESD(Endoscopic Submucosal Dissection) , EMR(Endoscopic Mucosal Resection), enteroscopy and other gastrointestinal endoscopic diagnosis and treatment were performed
  • The duration of anesthesia is more than 30 minutes, that is, from induction to withdrawal of anesthesia
  • ASA(American Society of Anesthesiologists) ≤ II 4.18kg/m2\<BMI\<30 kg/m2
  • Informed consent, voluntary participation in the experiment, and signed by the subject informed consent

Exclusion

  • ASA classification ≥ III;
  • History of previous lung or nasal surgery;
  • History of chronic obstructive pulmonary disease (COPD) or restrictive lung disease;
  • History of obstructive sleep apnea syndrome;
  • History of upper airway obstruction;
  • History of head and neck radiation therapy;
  • Significant nasal septum deviation;
  • Active infection (defined as a white blood cell count \>10\*10\^9 or a body temperature \>38°C);
  • Gastrointestinal perforation;
  • Combined use of other anesthetic methods or inhalation anesthetics outside of non-intubated intravenous anesthesia;
  • Concurrent other medical procedures besides the prescribed gastrointestinal endoscopic procedures, such as ERCP(Endoscopic Retrograde Cholangiopancreatography);
  • Severe communication disorders due to conditions like severe hearing impairment or dementia;
  • Disagreement with participation in the study.

Key Trial Info

Start Date :

February 18 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2025

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT06554678

Start Date

February 18 2024

End Date

March 1 2025

Last Update

March 14 2025

Active Locations (1)

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Northern Jiangsu People's Hospital

Yangzhou, Jiangsu, China, 225000