Status:

RECRUITING

Effect of Albumin Replacement on Oxygen Delivery in Sepsis Patients

Lead Sponsor:

Samsun University

Conditions:

Sepsis

Intensive Care Unit

Eligibility:

All Genders

18+ years

Brief Summary

Fluid resuscitation is a critical component of sepsis treatment. Research has shown that intravenous (IV) fluid therapy in sepsis positively impacts cardiac output and thereby oxygen (O2) delivery thr...

Detailed Description

Patients will be admitted from the emergency room, operating room or medical wards. After obtaining written consent from the patients or their guardians, patients who are followed up in the intensive ...

Eligibility Criteria

Inclusion

  • Followed up with a diagnosis of sepsis,
  • over 18 years old
  • Patients who were diagnosed with hypo-albuminemia after more than 4L/day fluid resuscitation and underwent albumin replacement

Exclusion

  • Consent is not given by the patient or his/her guardian,
  • The initial cause of shock was hypovolemic, cardiogenic or obstructive shock.
  • Pregnancy or suspected pregnancy
  • Peripheral limb or severe organ ischemia with peripheral artery disease
  • Cardiac functions cannot be evaluated optimally by transthoracic echocardiography
  • Patients who died within the first 24 hours after intensive care admission

Key Trial Info

Start Date :

November 15 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 15 2025

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT06556914

Start Date

November 15 2024

End Date

October 15 2025

Last Update

July 3 2025

Active Locations (1)

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Samsun University

Samsun, Ilkadım, Turkey (Türkiye), 55100