Status:
COMPLETED
Lidocaine Versus Fentanyl for Hemodynamic Stability
Lead Sponsor:
Theodor Bilharz Research Institute
Conditions:
Hypertension
Fentanyl
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
Hypertension is an important health challenge that affects millions of people across the world today and is a major risk factor for multiple system comorbidities. Intraoperative hypotension may lead t...
Detailed Description
Since post induction hypotension is mainly caused by anesthetic drugs, developing a technique for the induction of anesthesia that provides adequate hypnosis with stable hemodynamics during surgery is...
Eligibility Criteria
Inclusion
- ASA II, Hypertensive patients with the following criteria:
- Diagnosed with hypertension more than 5 years and on continuous medications.
- Controlled hypertension (systolic pressure \< 140 mm Hg and the diastolic \< 90 mm Hg).
- Age: 18-60 years of both sexes.
- Elective non cardiac surgery requiring general anesthesia.
Exclusion
- Uncontrolled hypertension (SPB \> 140 mm Hg) OR (DBP \< 90 mm HG).
- SVV (stroke volume variability) ≥ 13.
- Patients with suspected difficult intubation as judged by the attending anesthetist during the preoperative assessment and patients for whom an alternative device other than an endotracheal tube will be considered.
- Pregnancy.
- History of drug abuse.
- Obese patients (BMI ≥ 35kg/m2).
- Allergy to any of the used medications.
Key Trial Info
Start Date :
April 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06557473
Start Date
April 1 2023
End Date
July 1 2024
Last Update
August 23 2024
Active Locations (1)
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1
Theodor Bilharz Research Institute
Giza, Egypt