Status:
RECRUITING
Cardiovascular Health & Early Stress
Lead Sponsor:
Virginia Commonwealth University
Conditions:
Stress
Eligibility:
All Genders
9-30 years
Brief Summary
Childhood adversity is highly prevalent, with 59% of the U.S. population reporting at least one adverse childhood experience (ACE). Substantial evidence links childhood adversity to cardiometabolic di...
Detailed Description
Current knowledge supports that ACEs trigger emotional stress, anxiety, fear, and discomfort in the individual. Acute and intense mental stress leads to structural changes in the amygdala, prolonged a...
Eligibility Criteria
Inclusion
- Cohort 1
- Men and pre-menopausal women
- 18-30 years old
- Cohort 2
- males and females
- 9-17 years old
Exclusion
- Cohort 1
- Evidence of cardiovascular, pulmonary, renal, hepatic or cerebral diseases
- Evidence of pregnancy or currently nursing.
- Having a history of chronic pain
- Having a history of rheumatoid arthritis
- Cohort 2
- Evidence of cardiovascular, pulmonary, renal, hepatic or cerebral diseases
- Evidence of pregnancy or currently nursing.
- Having a history of chronic pain
- Having a history of rheumatoid arthritis
Key Trial Info
Start Date :
January 20 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06557707
Start Date
January 20 2022
End Date
December 1 2028
Last Update
September 4 2025
Active Locations (1)
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1
Virginia Commonwealth University
Richmond, Virginia, United States, 23298