Status:
NOT_YET_RECRUITING
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
Lead Sponsor:
Minia University
Conditions:
Dentin Hypersensitivity
Eligibility:
All Genders
20-40 years
Phase:
NA
Brief Summary
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticle...
Detailed Description
Hypersensitivity has been defined as the pain arising from exposed dentin, typically in response to chemical, thermal, tactile or osmotic stimuli that cannot be explained as arising from any other for...
Eligibility Criteria
Inclusion
- Hypersensitive areas on facial surfaces of the teeth (incisors, cuspids, bicuspids, and first molars with exposed cervical dentine)
- Areas with hard tissue erosion
- cuneiform defect, pathological abrasion.
- Gingival recession
- Good overall physical health
- Age between 20 to 40 years; and provision of written informed consent
Exclusion
- chipped teeth
- Defective restorations
- fractured un displaced cuspids
- deep dental caries
- deep periodontal pockets
- orthodontic appliances, dentures, or bridgework that would interfere with the evaluation of hypersensitivity.
- periodontal surgery within the previous 6 months.
- ongoing treatment with antibiotics and/or anti-inflammatory and/or analgesic drugs.
- ongoing treatment for tooth hypersensitivity, pregnancy, or lactation; heavy smoking and alcohol or drug abuse.
Key Trial Info
Start Date :
May 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06557980
Start Date
May 1 2025
End Date
October 1 2025
Last Update
May 11 2025
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