Status:

COMPLETED

Evaluation of Salivary Biomarker Levels in Individuals With Different Periodontal Conditions

Lead Sponsor:

Izmir Katip Celebi University

Conditions:

Periodontitis

Gingivitis

Eligibility:

All Genders

18-70 years

Brief Summary

In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body. Recent publications have investigated t...

Detailed Description

The aim of this clinical study is to comparatively examine the levels of IL-6, IL-8 and LIGHT Protein in saliva samples obtained from periodontally healthy individuals with gingivitis and periodontiti...

Eligibility Criteria

Inclusion

  • Systemically healthy participants.
  • At least twenty permanent teeth present in the oral cavity.
  • Non-smokers.
  • No medication for continuous use.
  • Not pregnant or breastfeeding.

Exclusion

  • Any oral or systemic disease.
  • Regular use of systemic medications.
  • Pregnancy or lactation.
  • Received periodontal treatment within the last 6 months.
  • Use of antibiotics, anti-inflammatory medications, or systemic corticosteroids in the last 6 months.
  • Smokers.

Key Trial Info

Start Date :

August 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 15 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06558136

Start Date

August 1 2024

End Date

October 15 2025

Last Update

November 25 2025

Active Locations (1)

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Izmir Katip Çelebi University Department of Periodontology

Izmir, İzmir, Turkey (Türkiye), 35640