Status:

NOT_YET_RECRUITING

Vibrotactile Coordinated Reset (vCR) for the Treatment of Advanced Parkinson's Disease Patients Who Have Previously Received vCR Stimulation

Lead Sponsor:

Stanford University

Conditions:

Parkinson Disease

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

The purpose of this study is to test the efficacy of vibrotactile coordinated reset(vCR) stimulation on human subject participants with advanced stage Parkinson's Disease who have previously received ...

Eligibility Criteria

Inclusion

  • Any adult age 18 and older
  • Idiopathic Parkinson's Symptoms between Hoehn and Yahr stages 2 to 4
  • Fluent in English
  • If patient is on medication that affects brain function or alters Electroencephalography (EEG) activity, the patient must feel comfortable going off this medication prior to EEG recording
  • Appropriate social support if required during an off state.
  • Comfortable with technology; can use a computer, check email, and access the internet; can initiate and engage in a virtual meeting for training and monitoring purposes.
  • Feels comfortable going off Parkinson's Disease(PD) related medication during in person study visits
  • Lives in the United States
  • Having previously been enrolled in a vCR pilot study

Exclusion

  • Any significant neuro-psychiatric problems, including acute confusional state, ongoing psychosis, or suicidal tendencies
  • Any current drug or alcohol abuse.
  • Participation in another drug, device, or biologics trial concurrently or within the preceding 30 days. Any other trial participation should be approved by the Principal Investigators.
  • Pregnancy, breast-feeding or wanting to become pregnant
  • Physical limitations unrelated to PD that would affect motor ratings
  • Craniotomy
  • Brain surgery
  • Patient is unable to communicate properly with staff (i.e., severe speech problems)
  • Excessive drooling
  • A type of hairstyle that would impede the use of an EEG cap
  • Sensory abnormalities of the fingertips
  • Patient is taking a medication that may cause significant withdrawal effects.
  • Presence or diagnosis of Essential Tremor, psychogenetic tremor, functional tremor and any other non- pathological or non-Parkinsonian tremors

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2027

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT06559098

Start Date

January 1 2025

End Date

September 1 2027

Last Update

September 5 2024

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