Status:

COMPLETED

Cryopreservation Medium With Apigenin on Post-thaw Human Sperm

Lead Sponsor:

Chulalongkorn University

Conditions:

Healthy

Eligibility:

MALE

18-45 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to compare the effect of apigenin supplementation in freezing medium with no apigenin supplementation in freezing medium on post-thaw human sperm motility. It will a...

Detailed Description

All normal semen samples from participants who give written informed consent and meet the eligibility requirements will be included in the study. Prepared semen samples were divided into 3 groups. 1....

Eligibility Criteria

Inclusion

  • Healthy men aged 18-45 years who can receive semen analysis services at the Reproductive Biology Unit, Chulalongkorn Hospital, Thai Red Cross Society
  • Normal semen analysis results according to the World Health Organization criteria (Volume ≥ 1.4 mL, Sperm concentration ≥ 16 million/mL, Total motility ≥ 42%, Progressive motility ≥ 30%)
  • Giving consent

Exclusion

  • A history of accidents, radiation to the testes, or a history of male reproductive system surgery
  • Undescended testis
  • Varicocele
  • A history of taking certain medications that affect sperm production, such as chemotherapy, hormones
  • Currently having sexually transmitted disease

Key Trial Info

Start Date :

October 28 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 3 2025

Estimated Enrollment :

57 Patients enrolled

Trial Details

Trial ID

NCT06560216

Start Date

October 28 2024

End Date

March 3 2025

Last Update

March 18 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Chulalongkorn Hospital

Bangkok, Thailand, 10330

2

Chulalongkorn University

Bangkok, Thailand, 10330