Status:

COMPLETED

Oral Contraceptive Consumption Timing and Cognition and Metabolism

Lead Sponsor:

University of Lincoln

Conditions:

Cognitive Change

Eligibility:

FEMALE

18-35 years

Phase:

NA

Brief Summary

The aim of this randomised-controlled trial is to examine whether the timing of oral contraceptive administration affects cognitive function, substrate metabolism and exercise performance. Participan...

Detailed Description

Reproductive hormones, such as oestrogen and progesterone, are known to affect cognitive function (i.e. thinking, learning and processing information) and substrate metabolism (i.e. how the body uses ...

Eligibility Criteria

Inclusion

  • Female
  • Aged 18-35 years
  • The use of the same oral contraceptive (30 micrograms ethinyl estradiol and 150mg levonorgestrel) for at least 6 months
  • Physically active and able to take part in treadmill-based exercise
  • Speak fluent English

Exclusion

  • Use of any other type of hormonal contraception
  • Aged \< 18 or \> 35 years
  • Poly-cystic ovarian syndrome
  • Endometriosis
  • Pregnant
  • Child birth or lactation in the previous 6 months
  • Body mass index \< 18.5 or \> 30 kg.m2
  • Any disorder known to affect metabolic health
  • History of head injury/neurological disorders
  • Use of any steroid-based medication or medications known to influence the central nervous system
  • History of psychiatric disorders such as major depression or an anxiety disorder
  • Smokers
  • Suffer from (or have suffered from) a heart complaint
  • Advised by medical professional to refrain from high intensity exercise
  • Current muscle or joint injury

Key Trial Info

Start Date :

January 17 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 20 2024

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT06560944

Start Date

January 17 2020

End Date

January 20 2024

Last Update

August 21 2024

Active Locations (1)

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1

Dan Martin

Lincoln, Lincolnshire, United Kingdom, LN6 7TS