Status:
RECRUITING
TBI Rehabilitation and Activation in Veterans
Lead Sponsor:
Northern California Institute of Research and Education
Collaborating Sponsors:
San Francisco Veterans Affairs Medical Center
VA Palo Alto Health Care System
Conditions:
Traumatic Brain Injury
Eligibility:
All Genders
50-89 years
Phase:
NA
Brief Summary
This trial will evaluate the impact of a multicomponent program (TBI Rehabilitation and Activation in Veterans; TRAIN-Vets) on improving cognitive function over an 8-month trial period in older Vetera...
Detailed Description
The purpose of the proposed trial is to evaluate the impact of a multicomponent training program (TRAIN-Vets) on improving cognitive function and other outcomes over an 8-month period in older Veteran...
Eligibility Criteria
Inclusion
- Veteran, age 50-89 years
- History (more than 6 months post injury) of mild or moderate TBI defined by the Ohio State University TBI Identification Method and DOD/VA Clinical Practice Guidelines for Definition of TBI
- Sufficient vision and hearing to allow cognitive testing
- Willingness to participate in water-based exercise program + cognitive training program for eight months
- Approval of primary medical provider to participate in a water-based exercise program
- Subjective cognitive complaints as evidenced by self-report
- English proficiency to allow for cognitive testing
- Internet connected device to participate in testing and cognitive training
Exclusion
- Current severe and unstable psychiatric disorder
- Diagnosis of dementia, Montreal Cognitive Assessment score less than 18, or delirium
- TBI within the past 6 months
- Acute illness or unstable chronic illness
- Current severe cardiac disease
- Severe TBI or open head injury
- Inability to exercise consistently
- Inability to read, verbalize understanding, and voluntarily sign the Informed Consent
Key Trial Info
Start Date :
May 12 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2028
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06562127
Start Date
May 12 2025
End Date
February 1 2028
Last Update
May 16 2025
Active Locations (2)
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1
VA Palo Alto Health Care System
Palo Alto, California, United States, 94304-1207
2
San Francisco VA Health Care System
San Francisco, California, United States, 94121