Status:
RECRUITING
fMRI Accelerated TMS Depression
Lead Sponsor:
Medical University of South Carolina
Collaborating Sponsors:
Foundation for the Advancement of Clinical TMS
Conditions:
Depression
Eligibility:
All Genders
18-65 years
Brief Summary
This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in ...
Detailed Description
The aim of this study is to use magnetic resonance imaging (MRI) to capture images of participants' brains and apply an image processing method called INSCAPE to assess brain states. This study will r...
Eligibility Criteria
Inclusion
- Age 18-65
- Have the capacity and ability to provide one's own consent in English and sign the informed consent document.
- DSM-IV diagnosis of MDD
Exclusion
- Unable to speak English.
- Contraindicated for MRI.
- Any current or recent untreated medical, neurological, or psychiatric conditions
- Metal implant devices in the head, heart, or neck.
- History of brain surgery.
- History of cortisol medication use or electroconvulsive therapy.
- Comorbidity with other psychiatric/neurological illnesses or personality disorders
- History of myocardial infarction or arrhythmia, bradycardia.
- Personal history of head injury, concussion, or self-report of moderate to severe traumatic brain injury.
- Individuals suffering from frequent/severe headaches.
- Moderate to severe alcohol or substance use disorder.
- Pregnancy
Key Trial Info
Start Date :
September 23 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 5 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06562153
Start Date
September 23 2024
End Date
August 5 2026
Last Update
October 16 2025
Active Locations (1)
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1
30 Bee Street
Charleston, South Carolina, United States, 29429