Status:
RECRUITING
Evaluation of the Reproducibility of a Fatigability Test Fitted to Patients With Spinal Muscular Atrophy
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Conditions:
Spinal Amyotrophy
Infantile Spinal Muscular Atrophy
Eligibility:
All Genders
6+ years
Phase:
NA
Brief Summary
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease caused by the degeneration of motor neurons in the anterior horn of the spinal cord, due to the absence of the SMN1 gene a...
Eligibility Criteria
Inclusion
- Genetically confirmed spinal muscular atrophy
- Age ≥ 6 years
- No orthopaedic surgery in the 6 months prior to inclusion
- Informed consent signed by the patient(s) or parent(s)/legal guardian(s) and assent of the patient
- Affiliated or beneficiary of a health insurance scheme (for inclusion in France)
Exclusion
- Other condition that may significantly interfere with the assessment of the SMA and which is clearly unrelated to the disease
- Other associated neurological disease
- Joint deformities that prevent correct and comfortable positioning with the various different measuring devices (thumb-index clamp, handgrip and QIF-test)
- Contraindication to transcranial magnetic stimulation
Key Trial Info
Start Date :
December 6 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06562283
Start Date
December 6 2024
End Date
October 1 2026
Last Update
December 19 2024
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
HCL - Hôpital Croix Rousse
Lyon, France
2
HFME - Hospices Civils de Lyon
Lyon, France
3
Aphp - Hopital Pitie Salpetriere
Paris, France
4
Unités de Myologie et de Médecine du Sport
Saint-Etienne, France, 42055