Status:
RECRUITING
Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
Lead Sponsor:
Dow University of Health Sciences
Conditions:
Effect of Drug
Eligibility:
All Genders
18-45 years
Phase:
PHASE4
Brief Summary
This study aims to compare the pain reduction efficacy of Trypsin-Chymotrypsin and Naproxen sodium after root canal treatment in patients with symptomatic irreversible pulpitis. A lot of patients suff...
Detailed Description
i. Background Prevention or management of pain, especially after root canal treatment, is of utmost importance to Endodontists. Non-steroidal anti-inflammatory drugs (NSAIDs) have been the most common...
Eligibility Criteria
Inclusion
- Both male and female, healthy patients (ASA class 1).
- Patients between the age group of 18-45 years.
- Patients who are appointed for endodontic treatment.
- Maxillary or mandibular teeth diagnosed with symptomatic irreversible pulpitis based on delayed responses to vitality tests.
Exclusion
- Patients who will require emergency dental treatment.
- Teeth with any form of peri-apical lesion will be excluded.
- Patient who have taken analgesics within 24 hours prior to the treatment.
- Patients with known hypersensitivity or allergy to any of the study medications.
- Patients with any systemic disease such as uncontrolled diabetes, gastric ulcers, bleeding disorders, or cardiovascular problems.
- Pregnant or lactating women and pediatric patients.
Key Trial Info
Start Date :
August 16 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06562816
Start Date
August 16 2024
End Date
January 31 2025
Last Update
November 4 2024
Active Locations (1)
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1
Dow University of Health Sciences
Karachi, Sindh, Pakistan, 74200