Status:
RECRUITING
Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism
Lead Sponsor:
University of Pennsylvania
Collaborating Sponsors:
American College of Surgeons
Conditions:
Hyperparathyroidism, Primary
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this study is to address surgical health equity in historically marginalized participants with primary hyperparathyroidism (PHPT). The main questions that this study aims to answer are, ho...
Detailed Description
Patients historically marginalized in Medicine are at increased risk of delayed care and undertreatment of PHPT, which can result in end-organ damage and reduced quality of life due to fatigue, brain ...
Eligibility Criteria
Inclusion
- Diagnosed with PHPT and not yet had parathyroidectomy who meet criteria for surgical treatment of PHPT (osteoporosis, fragility fracture, or evidence of vertebral compression fracture on spine imaging, renal involvement \[renal stone, silent nephrolithiasis on renal imaging, nephrocalcinosis, hypercalciuria (24-hour urine calcium level 400 mg/dL) with increased stone risk, or impaired renal function (glomerular filtration rate 60 mL/min)\], calcium 1 mg/dL above upper limit of normal, age less than 50)
- Qualify as a member of a racial or ethnic minority group (Black, Hispanic, Asian and Pacific Islander, Native American), lower socioeconomic neighborhoods (by zipcode), socially vulnerable (social determinants of health indicating financial strain, social vulnerability index in the top quartile 75%+ by zip code), or with underinsurance (Medicaid, Medicare, dual eligible, uninsured)
Exclusion
- Prior Parathyroidectomy
- End-stage Renal Disease
- Renal Transplant
- Vitamin D Deficiency
- Metastatic Disease
- Familial Hypocalciuric Hypercalcemia
- No Indication for Surgery
- Unable/Unwilling to provide consent
Key Trial Info
Start Date :
November 30 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
76 Patients enrolled
Trial Details
Trial ID
NCT06562881
Start Date
November 30 2025
End Date
December 1 2025
Last Update
November 20 2025
Active Locations (1)
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1
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104