Status:
TERMINATED
Combined Rehabilitation and Nutritional Support vs. Standard Care in In-Hospital Endocarditis Treatment
Lead Sponsor:
Johannes Grand
Conditions:
Infective Endocarditis
Endocarditis, Bacterial
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Infective endocarditis (IE) is associated with high morbidity and mortality. Patients with IE are affected by a lengthy hospitalization, leading to physical deconditioning and a rapid decline in physi...
Detailed Description
BACKGROUND: Infective endocarditis (IE) is a severe infection of the heart's inner lining, typically the valves, carrying high risks of acute heart failure and death. Patients often face extended hos...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA
- Clinical diagnosis of left-sided (native, prosthetic, or culture-negative) bacterial infective endocarditis mandating iv antibiotic treatment, including Cardiac Implantable Electronic Devices infections, irrespective of cause and location as defined by the ESC modified Duke Criteria
- Age ≥ 18 years
- EXCLUSION CRITERIA
- Hemodynamic instability (defined as a systolic blood pressure \<90 mmHg and lactate \>2.2 mmol/l measured in an arterial blood gas.
- Expected to be discharged within 3 days
- Immunocompromised due to severe combined immunodeficiency, HIV, or hematological malignancy
- Fungal endocarditis
- Pregnancy
- Unwilling or unable to sign or understand informed consent
Exclusion
Key Trial Info
Start Date :
February 19 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 7 2025
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT06563609
Start Date
February 19 2025
End Date
December 7 2025
Last Update
December 15 2025
Active Locations (1)
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1
Hvidovre Hospital
Hvidovre, Denmark, 2650