Status:

NOT_YET_RECRUITING

Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontitis

Lead Sponsor:

Cairo University

Conditions:

Periodontal Pocket

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

a clinical trial will be made to investigate the effect of locally applied injectable prf (iPRF) plus vitamin D on the periodontal pockets in stage III periodontitis patients

Detailed Description

in this clinical trial, the treatment of periodontal pockets in stage III periodontitis patients will be evaluated. the study participants will be divided in 3 groups: First group \>\> will be treate...

Eligibility Criteria

Inclusion

  • Patients with healthy systemic condition.
  • Adult patients ˃ 18 years old.
  • Patients with Stage III periodontitis.
  • Patients accept 3-month follow-up period (cooperative patients).
  • Patients provide an informed consent.

Exclusion

  • Presence of prosthetic crowns.
  • Extensive interproximal restorations.
  • Periodontal therapy within the last 12 months.
  • Having undergone surgical periodontal therapy or undergoing orthodontic treatment.
  • Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis.
  • The use of antibiotics or anti-inflammatory drugs 3-month prior to the procedure and till the end of 6-month of follow-up.
  • Smokers.
  • Pregnant females.

Key Trial Info

Start Date :

October 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT06570200

Start Date

October 1 2024

End Date

February 1 2026

Last Update

August 26 2024

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