Status:

RECRUITING

Retraining and Control Therapy (ReACT)- Adults

Lead Sponsor:

University of Alabama at Birmingham

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Convulsion, Non-Epileptic

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and th...

Detailed Description

Patients with PNES who are treated at the UAB FND clinic will have the option to complete additional study procedures. Participants will come to our laboratory for a baseline visit and 4 follow-up vis...

Eligibility Criteria

Inclusion

  • 19 years and older.
  • Diagnosis of psychogenic non-epileptic seizures by a medical doctor using video-EEG.

Exclusion

  • Comorbid Epilepsy
  • Less than 4 PNES per month
  • Other paroxysmal nonepileptic events (e.g. episodes related to hypoxic-ischemic phenomena, sleep disorders or migraine-associated disorders)
  • Participation in other therapy during the study
  • Severe intellectual disability
  • Severe mental illness (delusions/hallucinations)
  • Exclusion for CPT:
  • • Blood pressure \>130/80 mmHg

Key Trial Info

Start Date :

April 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06570954

Start Date

April 10 2025

End Date

December 31 2027

Last Update

June 6 2025

Active Locations (1)

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University of Alabama at Birmingham

Birmingham, Alabama, United States, 35294