Status:
RECRUITING
Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture
Lead Sponsor:
University of California, Irvine
Conditions:
Fibromyalgia
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
This study aims to see whether acupuncture can help fibromyalgia patients by giving them acupuncture treatment and seeing whether acupuncture helps enhance the effects of an opioid.
Detailed Description
The investigator hypothesizes that traditional acupuncture (TA) enhances binding of the MOR receptor which will then enhance the pain-reducing effects of opioids compared to sham acupuncture (SA). The...
Eligibility Criteria
Inclusion
- Are 18 - 80 years old
- have been diagnosed with Fibromyalgia for more than 6 months
- Are already using chronic, continuous opioid therapy, including but not limited to the use of Hydrocodone (Norco), Oxycodone (Percocet), morphine, methadone or Tylenol #3 daily
- Have moderate to excruciating pain at baseline, determined by a 5 or greater score on the Visual Analogue Scale (VAS)
Exclusion
- Are younger than 18 or older than 80 years old
- Have been diagnosed with a Substance Use Disorder (SUD)
- Pregnant
- Have an active litigation or worker's compensation case
- Have an active mental health diagnosis, such as bipolar disorder, psychosis, or suicidal ideation
- Are prescribed and actively using low dose Naltrexone . Have tried acupuncture in the last 6 months
Key Trial Info
Start Date :
March 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT06571110
Start Date
March 15 2025
End Date
December 1 2026
Last Update
November 12 2025
Active Locations (1)
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1
UCI Health Susan Samueli Integrative Health Institute
Irvine, California, United States, 92617