Status:
RECRUITING
Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Lead Sponsor:
Southeast University, China
Conditions:
ARDS, Human
Ventilator-Induced Lung Injury
Eligibility:
All Genders
Phase:
NA
Brief Summary
Reduced diaphragmatic activity during mechanical ventilation can lead to diaphragmatic disuse atrophy, atelectasis, increased lung stress and strain, and hemodynamic impairment. This, in turn, may pro...
Detailed Description
Mechanical ventilation is an important treatment for patients with acute hypoxemic respiratory failure (AHRF). However, reduced diaphragmatic activity during mechanical ventilation can lead to diaphra...
Eligibility Criteria
Inclusion
- Adult ARDS patients undergoing controlled mechanical ventilation
- The duration of endotracheal intubation \< 48 hrs
Exclusion
- Neurological condition affecting motor neuron or muscle (e.g. ALS)
- Paralysis of the phrenic nerve
- Proven or suspected spinal cord injury
- Conditions that limit diaphragm movement
- Patients with Implanted cardiac support systems (pacemaker, implanted defibrillator)
- Patients with implanted medical pumps
- Pregnancy
- Patients with skin lesions, infections or strictures in throat/neck area
- Patients with metallic implants
- Refusal to sign informed consent
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 30 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06572280
Start Date
August 1 2024
End Date
January 30 2025
Last Update
August 27 2024
Active Locations (1)
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1
Zhongda Hospital, School of Medicine, Southeast University
Nanjing, Jiangsu, China, 210009