Status:
COMPLETED
Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
Lead Sponsor:
Tanta University
Conditions:
Open
Laparoscopic
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To prospectively compare the perioperative, morphological and functional outcomes on short and medium term between laparoscopic (LP) and open pyeloplasty (OP) patients.
Detailed Description
Pelvi-ureteric junction obstruction (PUJO) is defined as a functionally significant impairment of the flow of urine from the kidney's renal pelvis into the proximal ureter. Open pyeloplasty (OP) has ...
Eligibility Criteria
Inclusion
- All adult patients (above 18 years old) with primary pelvi-ureteric junction obstruction indicated for active intervention as
- Symptoms such as recurrent flank pain, recurrent urinary tract infection and rarely hypertension.
- Breakthrough urinary tract infections while on prophylactic antibiotics.
- Increasing renal antero-posterior diameter, or decreasing renal parenchymal thickness by ultrasound.
- Low or decreasing differential renal function, but above 10%.
Exclusion
- Patients having poor ipsilateral renal function \< 10%.
- Patients with previous pelvi-ureteric junction obstruction repair.
- Associated renal stones.
- Patients unfit for surgery according to American Society of Anesthesiologists classification.
- Contraindications for laparoscopy as (marked obesity, large ventral hernias, gross coagulopathy, abdominal wall sepsis, vertebral deformities…).
- Pediatric patients.
- Pregnant women.
- Vesicoureteral reflux.
- Congenital renal anomalies as (horse- shoe kidney, pelvic kidney, mal- rotated kidney ...).
- Single functioning kidney.
- Malignancy.
- Refusal of written consent.
Key Trial Info
Start Date :
October 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2023
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT06572371
Start Date
October 1 2022
End Date
October 1 2023
Last Update
August 27 2024
Active Locations (1)
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1
Tanta University
Tanta, ElGharbia, Egypt, 31527