Status:

ACTIVE_NOT_RECRUITING

LIver FRAilty Management IN Cirrhosis (LIFRAMIN)

Lead Sponsor:

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Conditions:

Sarcopenia

Cirrhosis, Liver

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to compare food for special medical purposes (Aminolife Plus, by Piemme Pharmatech) vs. placebo in improving muscle mass and function in a cohort of cirrhotic patien...

Detailed Description

patients will be randomly allocated within the two groups: 1. nutritional counselling according to guidelines + Aminolife plus 20 g/day (4 scoops) vs. 2. nutritional counselling according to guidelin...

Eligibility Criteria

Inclusion

  • Patients affected by Liver cirrhosis
  • at any stage of Child (A-B-C) with or without hepatocarcinoma
  • SARC-F suggestive of risk of sarcopenia
  • Age \> 18 years
  • Ability to perform Liver Frailty Index test
  • Informed consent to participate in the study.

Exclusion

  • SARC-F not suggestive of sarcopenia
  • inability to perform Liver Frailty Index test
  • absence of informed consent

Key Trial Info

Start Date :

August 2 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 30 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06573229

Start Date

August 2 2024

End Date

October 30 2025

Last Update

August 13 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Emanuele Rinninella

Rome, Italy, 00168