Status:
COMPLETED
Dietary Intervention for Low Free Sugars in Children With Non-alcoholic Fatty Liver Disease
Lead Sponsor:
China Medical University, China
Conditions:
NAFLD
Low-free Sugar Dietary
Eligibility:
All Genders
5-14 years
Phase:
NA
Brief Summary
A 48-week dietary intervention program was conducted in children aged 5-14 years with a diagnosis of NAFLD, who were randomized into a low free sugar diet group and a regular diet group. The primary o...
Eligibility Criteria
Inclusion
- Age: above 5 years old and below 14 years old;
- Guardian's consent and signing of informed consent;
- WHO growth and development curves as the reference standard, overweight is defined as BMI greater than or equal to the 85th percentile of the WHO growth curves for children, and obesity is defined as BMI greater than or equal to the 95th percentile of the WHO growth curves for children;
- Liver imaging performance meets the diagnostic criteria of diffuse fatty liver.
Exclusion
- Age \<5 years or \>14 years;
- Previous history of alcohol consumption;
- Non-cooperation with the study, inability to comply with the study treatment or study visit.
- Past or active hepatitis B virus infection;
- Past or active hepatitis C virus infection;
- Chronic or acute liver failure;
- Cholestasis;
- Hepatomegaly;
- Cystic fibrosis;
- α1-antitrypsin deficiency;
- Autoimmune hepatitis;
- Tyrosinemia;
- Galactosemia or any recognized liver disease, any physical condition deemed by a physician to be unable to complete the trial. Physical Condition.
Key Trial Info
Start Date :
October 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2022
Estimated Enrollment :
146 Patients enrolled
Trial Details
Trial ID
NCT06579729
Start Date
October 1 2018
End Date
April 1 2022
Last Update
August 30 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
China Medical University
Shenyang, China