Status:

RECRUITING

The TRICURE EU Pivotal Study

Lead Sponsor:

TRiCares

Conditions:

Tricuspid Valve Regurgitation

Heart Valve Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Prospective, multi-center study to assess safety and performance of the TRiCares Topaz Tricuspid Valve Replacement System

Detailed Description

The study is a multi-center, prospective single arm study designed to evaluate the safety and performance of the TRiCares Topaz Tricuspid Valve Replacement System.

Eligibility Criteria

Inclusion

  • Adult patients
  • Tricuspid regurgitation grade 3 (severe) on a scale of 0 (none) to 5 (torrential)
  • Institutional Heart Team evaluates patient as being at increased operative risk

Exclusion

  • Patient in need of emergent intervention
  • Patient who is hemodynamically unstable
  • Anatomical contraindications for implantation with study device
  • Patient who is currently participating in another clinical investigation where the primary endpoint was not reached yet

Key Trial Info

Start Date :

August 29 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2030

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06581471

Start Date

August 29 2024

End Date

December 30 2030

Last Update

September 12 2025

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Algemeen Stedelijk Ziekenhuis

Aalst, Belgium, 9300

2

ZNA Middelheim

Antwerp, Belgium

3

UZ Brussel

Brussels, Belgium, 1090

4

Cliniques Universitaires Saint-Luc UCL

Brussels, Belgium