Status:
COMPLETED
Multicenter Comparison of Thermal Ablation Versus Thyroid Lobectomy for Subcapsular Papillary Thyroid Microcarcinoma
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Thyroid Cancer
Papillary Thyroid Microcarcinoma
Eligibility:
All Genders
18+ years
Brief Summary
To compare the clinical outcomes of Thermal ablation with those of thyroid lobectomy in patients with subcapsular papillary thyroid microcarcinoma.
Detailed Description
The global incidence of papillary thyroid microcarcinoma (PTMC) has increased rapidly in recent decades because of improved ultrasound (US) detection and fine needle aspiration biopsy and has primaril...
Eligibility Criteria
Inclusion
- a unifocal papillary thyroid carcinoma (PTC) diagnosed by fine-needle aspiration or core-needle biopsy;
- tumor with a maximum diameter of ≤ 10 mm detected on ultrasound;
- tumor located within ≤ 2mm from the thyroid capsule (with or without tumor-associated capsular bulging or capsular discontinuity);
- absence of clinical or imaging evidence of gross ETE (involvement of strap muscles, obtuse angles between the tumor and trachea/esophagus, protrusion into the tracheoesophageal groove, and invasion into other neck structures);
- no clinical or imaging evidence suggesting lymph node metastasis or distant metastasis
Exclusion
- aggressive subtypes of PTC (aggressive subtypes of PTC includes the tall cell, columnar cell, solid, and hobnail variants);
- multifocal PTMC;
- history of neck surgery or TA;
- a follow-up period of \< 24 months;
- incomplete follow-up data, or poor-quality pre-treatment ultrasound images
Key Trial Info
Start Date :
January 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2024
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT06583057
Start Date
January 1 2019
End Date
July 31 2024
Last Update
September 3 2024
Active Locations (1)
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1
ChinaPLAGH
Beijing, Beijing Municipality, China, 100853