Status:

COMPLETED

Effects of Indena's Virtiva® Plus Ginkgo Biloba Extract on Stress, and Cognitive Performance

Lead Sponsor:

Applied Science & Performance Institute

Conditions:

Stress

Mood

Eligibility:

All Genders

50-70 years

Phase:

NA

Brief Summary

This is a randomized, double-blind, 5-week intervention clinical study that aims to investigate the dose-dependent effects of Virtiva® Plus on stress, and cognitive performance in participants experie...

Detailed Description

Enrollment (Week -4 to Week -3): After obtaining written informed consent participants will undergo screening to ensure they are free of cardiovascular-, neurological-, hepatic-, renal-, metabolic dis...

Eligibility Criteria

Inclusion

  • Male or female
  • Aged 50 to 70 years (both limits inclusive)
  • Body mass index (BMI) value of 18.5-29.99 kg/m2
  • Willing and able to give written informed consent
  • Able to read, understand, sign and date the informed consent document (English only)
  • Able and willing to comply with the schedule visit(s) and study requirements.
  • Willing to consume the investigational study product 2 times per day for 5 weeks.
  • Willing to maintain a habitual diet and avoid changes during the study period (for example, intermittent fasting, ketogenic diet, Atkins diet, meatless diet, etc.).
  • Willing to cease from consuming cognitive enhancement supplements 7 days prior to and after the study commencement, until the end of the study.

Exclusion

  • Developmental disability or cognitive impairment that would preclude adequate comprehension of the informed consent form and/or ability to follow study subject requirements and/or record the necessary study measurements.
  • History of cardiovascular disease (i.e., myocardial infarction, hypertension, hypercholesterolemia, peripheral vascular disease, other)
  • History of neurological disorders (Parkinson's, Amyotrophic lateral sclerosis, epilepsy, spinal cord injury resulting in inability to use upper extremities, other)
  • History of gastrointestinal disorders that could lead to uncertain absorption of the study supplements, (i.e., inflammatory bowel disease, ulcerative colitis, Crohn's disease, colostomy, or eating disorder)
  • History of kidney or liver disease
  • History of metabolic disorders (diabetes, metabolic syndrome, other)
  • History or current malignancy
  • Receiving chemotherapy agents or radiation treatments
  • Diagnosis of a terminal illness
  • Pregnancy or has breast fed within 3 months prior to enrollment
  • Use of prescription medications that impact digestion (i.e., proton pump inhibitor medications, other)
  • History or current alcohol or drug abuse
  • Has significant concurrent illnesses (controlled or uncontrolled), such as lupus, hepatitis B/C, HIV, serious mental health illness such as dementia or schizophrenia; psychiatric hospitalization in the past two years, or other, which in the opinion of the investigator, such condition might be aggravated as a result of treatment
  • The investigator feels that for any reason the subject is not eligible to participate in the study

Key Trial Info

Start Date :

January 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 4 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06583941

Start Date

January 10 2025

End Date

April 4 2025

Last Update

September 16 2025

Active Locations (1)

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The Applied Science and Performance Institute

Tampa, Florida, United States, 33634