Status:

RECRUITING

Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT)

Lead Sponsor:

University of Michigan

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

NYU Silver School of Social Work

Conditions:

Depression

Eligibility:

All Genders

50+ years

Phase:

NA

Brief Summary

This study is a randomized Type I hybrid effectiveness-implementation trial aimed at evaluating the effectiveness of Empower@Home, an internet-delivered cognitive-behavioral therapy (CBT) program supp...

Detailed Description

This study is a randomized Type I hybrid effectiveness-implementation trial designed to evaluate the clinical effectiveness and implementation process of Empower@Home, an internet-delivered cognitive-...

Eligibility Criteria

Inclusion

  • (1) be receiving or eligible to receive services at the recruitment sites
  • (2) read and speak English
  • (3) be at least 50 years old
  • (4) have at least moderate depressive symptoms at screening (≥ 8 on the Patient Health Questionnaire-9 \[PHQ-9\]).
  • (5) Participants who are NOT currently receiving outside therapy must agree NOT to start outside therapy during study participation. Participants who are currently receiving outside therapy must agree NOT to increase their outside therapy frequency during study participation.

Exclusion

  • (1) probable dementia based on the Blessed Orientation and Memory Scale.
  • (2) moderate or high risk of suicide based on the 6-item Columbia-Suicide Severity Rating Scale
  • (3) a terminal illness with less than six months to live or unstable physical health conditions based on self-report
  • (4) a diagnosis of a psychotic disorder like schizophrenia or bipolar disorder based on self-report and medical chart review
  • (5) severe vision impairment based on self-report (i.e., legally blind)
  • (6) current substance use disorders or receiving substance use treatment.
  • (7) currently receiving outside therapy more frequently than once a month or have started a new therapy treatment less than 3 months ago

Key Trial Info

Start Date :

October 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2029

Estimated Enrollment :

256 Patients enrolled

Trial Details

Trial ID

NCT06584422

Start Date

October 1 2024

End Date

July 1 2029

Last Update

November 21 2025

Active Locations (1)

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1

University of Michigan

Ann Arbor, Michigan, United States, 48109