Status:
RECRUITING
Detecting Cardiac Thrombi in Acute Ischemic Stroke on Cardiac CT Versus Transoesophageal Echocardiography
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Ischemic Stroke
Cardioembolic Stroke
Eligibility:
All Genders
18+ years
Brief Summary
Rationale: Cardiac CT acquired during the acute stroke imaging protocol (acute cardiac CT) has recently been shown to have a superior diagnostic yield than transthoracic echocardiography, which is cu...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Clinical diagnosis of acute ischemic stroke
- Written informed consent from patient or representative
- Radiological diagnosis of cardiac thrombus in the LA, including the LAA, on cardiac CT acquired during the initial stroke imaging protocol.
Exclusion
- Patients with a diagnosis other than acute ischemic stroke, such as: transient ischemic attack, intracerebral haemorrhage, subarachnoid haemorrhage, epilepsy, tumor.
- Absolute contraindication for TEE:
- Perforated viscus
- Esophageal stricture
- Esophageal tumor
- Esophageal perforation, laceration
- Esophageal diverticulum
- Active upper GI bleed
- Absolute contraindication for repeat cardiac CT
- Documented previous severe reaction to iodinated contrast media, including anaphylaxis, angioedema and bronchospasm.
- Severely impaired kidney function defined as estimated glomerular filtration rate of 30 mL/min/1.73 m2.
Key Trial Info
Start Date :
August 19 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT06585228
Start Date
August 19 2024
End Date
October 1 2026
Last Update
February 3 2025
Active Locations (1)
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1
Amsterdam University Medical Center (UMC)
Amsterdam, North Holland, Netherlands, 1105AZ