Status:

NOT_YET_RECRUITING

Semi-elemental Versus Polymeric EEN in the Preoperative Optimization for Patients with CD

Lead Sponsor:

Wei Zhou

Conditions:

Crohn Disease

Nutrition Disorders

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Growing evidence has shown that exclusive enteral nutrition (EEN) plays an important role in the preoperative optimization for patients with Crohn's disease (CD). However, the efficacy and safety of d...

Detailed Description

Growing evidence has shown that exclusive enteral nutrition (EEN) plays an important role in the preoperative optimization for patients with Crohn's disease (CD). However, the efficacy and safety of d...

Eligibility Criteria

Inclusion

  • elective bowel resection for Crohn's disease;
  • preoperative diagnosis of Crohn's disease;
  • age between 18 to 65 years old;
  • malnutrition;
  • the Crohn's disease activity index over 150;
  • nasal feeding.

Exclusion

  • emergency surgery;
  • preoperative exclusive enteral nutrition before three months;
  • can not tolerate enteral nutrition;
  • less than 6 weeks of exclusive enteral nutrition;
  • preoperative corticosteroids within 3 months;
  • history of gastrointestinal surgery;
  • isolated colon disease;
  • metabolic disease (diabetes, hyperthyroidism).

Key Trial Info

Start Date :

October 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2025

Estimated Enrollment :

304 Patients enrolled

Trial Details

Trial ID

NCT06587178

Start Date

October 1 2024

End Date

December 30 2025

Last Update

September 19 2024

Active Locations (1)

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1

Wei Zhou

Hangzhou, Zhejiang, China, 310016