Status:
NOT_YET_RECRUITING
Changes in Renal Perfusion During Hemodialysis in Patients with End-stage Renal Disease
Lead Sponsor:
Yuanjun Yang
Conditions:
End-stage Renal Disease
Eligibility:
All Genders
18+ years
Brief Summary
Residual renal function (RRF) characteristically declines after patients with end-stage renal disease (ESRD) initiate dialysis. Although RRF preservation correlates with improved patient\'s qu...
Detailed Description
Hemodialysis (HD) is the primary renal replacement therapy for patients with end-stage renal disease. However, residual renal function (RRF) characteristically declines after these individuals start d...
Eligibility Criteria
Inclusion
- Age ≥ 18 years;
- Clinical diagnosis of end-stage renal disease requiring long-term hemodialysis treatment, with dialysis duration ≤ 3 months;
- Urine output \> 500ml/day or GFR \> 3ml/min/1.72m2;
- Signed and dated informed consented is obtained.
Exclusion
- Presence of vascular access dysfunction (blood flow rate \< 180ml/min);
- Severe heart failure;
- Active infection;
- Infectious disease;
- Patients with severe anemia;
- Patients with polycystic kidney disease;
- Expected dialysis duration \< 6 months;
- Pregnancy or lactation women;
- Patients who are participating in other clinical studies, or who have participated in other clinical studies within 3 months prior to enrollment;
- Unwillingness to be followed up or poor adherence to treatment;
- Other circumstances that the investigator considers unsuitable for enrolment.
Key Trial Info
Start Date :
September 5 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 3 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06587997
Start Date
September 5 2024
End Date
September 3 2026
Last Update
September 19 2024
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