Status:

RECRUITING

Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy

Lead Sponsor:

Sun Yat-sen University

Conditions:

Graves Ophthalmopathy

Surgery

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

To investigate the efficacy and safety of modified deep lateral wall decompression and/or medial wall decompression for Moderate-to-severe Grave's Ophthalmopathy.

Detailed Description

The purpose of the study is to evaluate the effectiveness and complications of modified deep lateral wall decompression and medial wall decompression, in order to develop a standardized technical appr...

Eligibility Criteria

Inclusion

  • EUGOGO/NOSPECS grade was moderate-to-severe thyroid associate ophthalmopathy;
  • CAS≤3 score;
  • stable thyroid function for at least 6 months;
  • able and willing to participate in clinical trials and ensure regular follow-up;

Exclusion

  • any uncontrollable clinical problems (severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumors);
  • B-ultrasound or CT, MRI found other diseases causing exophthalmos (intraorbital space occupying lesion, inflammatory pseudotumor, neurofibroma, etc.);
  • uveitis, glaucoma, high myopia, diabetic retinopathy and other eye diseases
  • those who were considered by the researchers to be excluded

Key Trial Info

Start Date :

September 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06588764

Start Date

September 1 2024

End Date

January 1 2026

Last Update

September 19 2024

Active Locations (1)

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1

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China, 510000