Status:

NOT_YET_RECRUITING

Trancriptomics and Lipidomics of Epicardial Ectopic Fat

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Type 2 Diabetes

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Cohort studies have shown that patients with obesity associated with metabolic abnormalities (metabolically unhealthy obesity) have an accumulation of ectopic fat deposits (EDF) linked to subcutaneous...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for T2D/DGE patient:
  • Adult patient of legal age included in the Angiosafe T2D multicenter study, having consented to the use of the data collected for research purposes.
  • Patient who has signed the GENTLE informed consent form.
  • Patient not objecting to re-use of data and samples collected in the Angiosafe T2D study
  • Patient with type 2 diabetes according to ADA recommendations
  • Age at diagnosis of diabetes less than or equal to 40 years and epicardial fat volume greater than 72 mL\*.
  • Patient beneficiary or affiliated to a social security scheme
  • Inclusion Criteria for control patient:
  • Adult patient of legal age included in the Angiosafe T2D multicenter study, having consented to the use of the data collected for research purposes.
  • Patient who has signed the GENTLE informed consent form.
  • Patient not objecting to re-use of data and samples collected in the Angiosafe T2D study
  • Patient with type 2 diabetes according to ADA recommendations
  • Age at diagnosis of diabetes greater than 40 and/or epicardial fat volume less than 72 mL
  • Patient beneficiary or affiliated to a social security scheme
  • Exclusion Criteria:
  • Type 1 diabetic patient
  • Patient with monogenic diabetes
  • Patient with diabetes secondary to pancreatic disease
  • Pregnant or breast-feeding women, patients under guardianship, deprived of liberty.

Exclusion

    Key Trial Info

    Start Date :

    October 1 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    April 1 2027

    Estimated Enrollment :

    84 Patients enrolled

    Trial Details

    Trial ID

    NCT06590415

    Start Date

    October 1 2024

    End Date

    April 1 2027

    Last Update

    September 19 2024

    Active Locations (1)

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    1

    Assistance Publique - Hôpitaux de Marseille

    Marseille, France, 13005